References
- Inflammatory bowel disease and irritable bowel syndrome: similarities and differences. Barbara, Cremon, and Stanghellini, 2014. Curr Opin Gastroenterol.
- Role for intestinal CYP2E1 in alcohol-induced circadian gene-mediated intestinal hyperpermeability. Forsyth et al., 2013. Am J Physiol Gastrointest Liver Physiol.
Expressions of tight junction proteins Occludin and Claudin-1 are under the circadian control in the mouse large intestine: implications in intestinal permeability and susceptibility to colitis - PubMed. (2014, May 20). PubMed. https://doi.org/10.1371/journal.pone.0098016
- Disruption of the Circadian Clock in Mice Increases Intestinal Permeability and Promotes Alcohol-Induced Hepatic Pathology and Inflammation. Summa et al., 2013. PLoS One.
- Exercise regulation of intestinal tight junction proteins. Zuhl et al., 2014. Br J Sports Med.
- Advances in coeliac disease. Lundin and Sollid, 2014 Curr Opin Gastroenterol.
- Definition and epidemiology of functional gastrointestinal disorders. Corazziari, 2004. Best Pract Res Clin Gastroenterol.
- Diagnosis of IBS: symptoms, symptom-based criteria, biomarkers or ‘psychomarkers’? Sood, Law, and Ford, 2014. Nat Rev Gastroenterol Hepatol.
- Global prevalence of and risk factors for irritable bowel syndrome: a meta-analysis. Lovell and Ford, 2012. Clin Gastroenterol Hepatol.
- The leaky gut of alcoholism: possible route of entry for toxic compounds. Bjarnason, Peters, and Wise, 1984. Lancet.
- Intestinal Permeability in Inflammatory Bowel Disease: Pathogenesis, Clinical Evaluation, and Therapy of Leaky Gut. Michielan and D'Inca, 2015. Mediators Inflamm.
- Tight junctions/adherens junctions: basic structure and function. Niessen, 2007. J Invest Dermatol.
- Alcohol and the Intestine. Patel et al., 2015. Biomolecules.
- Gut permeability, intestinal morphology, and nutritional depletion. van der Hulst et al., 1998. Nutrition.
- Intestinal barrier function: molecular regulation and disease pathogenesis. Groschwitz and Hogan, 2009. J Allergy Clin Immunol.
- Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders. Kelly et al., 2015. Front Cell Neurosci.
Are toxins flushed out of the brain during sleep? - Harvard Health. (2021, July 1). Harvard Health. https://www.health.harvard.edu/mind-and-mood/are-toxins-flushed-out-of-the-brain-during-sleep
Anxiety overload - Harvard Health. (2023, March 1). Harvard Health. https://www.health.harvard.edu/mind-and-mood/anxiety-overload
Does inflammation contribute to infertility? - Harvard Health. (2023, February 10). Harvard Health. https://www.health.harvard.edu/blog/does-inflammation-contribute-to-infertility-202302102888
Defining dysbiosis and its influence on host immunity and disease. Petersen and Round, 2014. Cell Microbiol.
- Revised Estimates for the Number of Human and Bacteria Cells in the Body. Sender, Fuchs, and Milo, 2016. PLoS Biol.
- Microbial ecology of the gastrointestinal tract. Savage, 1977. Annu Rev Microbiol.
- Development of the gut microbiota in infancy and its impact on health in later life. Tanaka and Nakayama, 2017. Allergol Int.
- Meconium microbiota types dominated by lactic acid or enteric bacteria are differentially associated with maternal eczema and respiratory problems in infants. Gosalbes et al., 2013. Clin Exp Allergy.
- Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns. Dominguez-Bello et al., 2010. Proc Natl Acad Sci U S A.
- Cesarean delivery is associated with celiac disease but not inflammatory bowel disease in children. Decker et al., 2010. Pediatrics
- Fiber-utilizing capacity varies in Prevotella- versus Bacteroides-dominated gut microbiota. Chen et al., 2017. Sci Rep.
- Linking long-term dietary patterns with gut microbial enterotypes. Wu et al., 2011. Science.
- A core human microbiome as viewed through 16S rRNA sequence clusters. Huse et al., 2012. PLoS One.
- Building a second brain in the bowel. Avetisyan et al., 2015. J Clin Invest.
- The enteric nervous system. Sasselli, Pachnis, and Burns, 2012. Dev Biol.
- The enteric nervous system and neurogastroenterology. Furness, 2012. Nat Rev Gastroenterol Hepatol.
- Gutsy Moves: The Amygdala as a Critical Node in Microbiota to Brain Signaling. Cowan et al., 2018. Bioessays.
- The Vagus Nerve in the Neuro-Immune Axis: Implications in the Pathology of the Gastrointestinal Tract. Bonaz, Sinniger, and Pellissier, 2017. Front Immunol.
- The effects of peripheral vagal nerve stimulation at a memory-modulating intensity on norepinephrine output in the basolateral amygdala. Hassert, Miyashita, and Williams, 2004. Behav Neurosci.
- Nutrigenetics and nutrigenomics: viewpoints on the current status and applications in nutrition research and practice. Fenech et al., 2011. J Nutrigenet Nutrigenomics.
- Lactase Non-persistence and Lactose Intolerance. Bayless, Brown, and Paige, 2017. Curr Gastroenterol Rep.
- Clinical implications of lactose malabsorption versus lactose intolerance. Levitt, Wilt, and Shaukat, 2013. J Clin Gastroenterol.
- Earliest date for milk use in the Near East and southeastern Europe linked to cattle herding. Evershed et al., 2008. Nature.
- New fossils from Jebel Irhoud, Morocco and the pan-African origin of Homo sapiens. Hublin et al., 2017. Nature.
- World-wide distributions of lactase persistence alleles and the complex effects of recombination and selection. Liebert et al., 2017. Hum Genet.
- Convergent adaptation of human lactase persistence in Africa and Europe. Tishkoff et al., 2007. Nat Genet.
- Nutrigenomics: definitions and advances of this new science. Sales, Pelegrini, and Goersch, 2014. J Nutr Metab.
- DNA methylation: superior or subordinate in the epigenetic hierarchy? Jin, Li, and Robertson, 2011. Genes Cancer.
- Epigenetics: the science of change. Weinhold, 2006. Environ Health Perspect.
- Epigenetics and miRNAs in the diagnosis and treatment of multiple sclerosis. Koch et al., 2013. Trends Mol Med.
- Vitamin D receptor negatively regulates bacterial-stimulated NF-kappaB activity in intestine. Wu et al., 2010. Am J Pathol.
- Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Kobayashi et al., 2005. Science.
- Do bacteria shape our development? Crosstalk between intestinal microbiota and HPA axis. de Weerth, 2017. Neurosci Biobehav Rev.
- The microbiome: A key regulator of stress and neuroinflammation. Rea, Dinan, and Cryan, 2016. Neurobiol Stress.
- Multiple sclerosis, relapses, and the mechanism of action of adrenocorticotropic hormone. Ross et al., 2013. Front Neurol.
- Melancholic microbes: a link between gut microbiota and depression? Dinan and Cryan, 2013. Neurogastroenterol Motil.
- Integrative Therapies in Anxiety Treatment with Special Emphasis on the Gut Microbiome. Schnorr and Bachner, 2016. Yale J Biol Med.
- Bi-directionality of Brain-Gut Interactions in Patients With Inflammatory Bowel Disease. Gracie et al., 2018. Gastroenterology.
- Impact of psychological stress on irritable bowel syndrome. Qin et al., 2014. World J Gastroenterol.
- Altered neuro-endocrine-immune pathways in the irritable bowel syndrome: the top-down and the bottom-up model. Stasi et al., 2012. J Gastroenterol.
- Structure, production and signaling of leptin. Münzberg and Morrison, 2015. Metabolism.
- Role of leptin in energy expenditure: the hypothalamic perspective. Pandit, Beerens, and Adan, 2017. Am J Physiol Regul Integr Comp Physiol.
- A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction. Clément et al., 1998. Nature.
- Ghrelin: much more than a hunger hormone. Pradhan, Samson, and Sun, 2013. Curr Opin Clin Nutr Metab Care.
- Ghrelin’s second life: from appetite stimulator to glucose regulator. Verhulst and Depoortere, 2012. World J Gastroenterol.
- Ghrelin mimics fasting to enhance human hedonic, orbitofrontal cortex, and hippocampal responses to food. Goldstone et al., 2014. Am J Clin Nutr.
- Appetite regulation and weight control: the role of gut hormones. Perry and Wang, 2012. Nutr Diabetes.
- Reward mechanisms in obesity: new insights and future directions. Kenny, 2011. Neuron.
- Food reward system: current perspectives and future research needs. Alonso-Alonso et al., 2015. Nutr Rev.
- Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats. Johnson and Kenny, 2010. Nat Neurosci.
- Incentive sensitization by previous amphetamine exposure: increased cue-triggered “wanting” for sucrose reward. Wyvell and Berridge, 2001. J Neurosci.
- Is dopamine a physiologically relevant mediator of feeding behavior? Palmiter, 2007. Trends Neurosci.
- Intraventricular insulin increases dopamine transporter mRNA in rat VTA/substantia nigra. Figlewicz et al., 1994.
- Leptin receptor signaling in midbrain dopamine neurons regulates feeding. Hommel et al., 2006. Neuron.
- Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite. Abizad et al., 2006. J Clin Invest.
- Gut microbiota and GLP-1. Everard and Cani, 2014. Rev Endocr Metab Disord.
- Serotonin, tryptophan metabolism and the brain-gut-microbiome axis. O'Mahony et al., 2015. Behav Brain Res.
- Minireview: Gut Microbiota: The Neglected Endocrine Organ. Clarke et al., 2014. Mol Endocrinol.
- Long non-coding RNAs as regulators of the endocrine system. Knoll, Lodish, and Sun, 2015. Nat Rev Endocrinol.
- Serotonin: from top to bottom. Fidalgo, Ivanov, and Wood, 2013. Biogerontology.
- Peripherally administered 5-hydroxytryptamine elicits the full behavioural sequence of satiety. Edwards and Stevens, 1991. Physiol Behav.
- Obesity and Overweight. World Health Organisation Retrieved Jan 2020.
- Obesity and diabetes. Riobó Serván, 2013. Nutr Hosp.
- The mechanisms linking obesity to colon cancer: An overview. Tarasiuk et al., 2018. Obes Res Clin Pract.
- Obesogenic environments: environmental approaches to obesity prevention. Lipek et al., 2015. J Pediatr Endocrinol Metab.
- The genetics of human obesity. Xia and Grant, 2013. Ann N Y Acad Sci.
- The genetics of obesity: FTO leads the way. Fawcett and Barroso, 2010. Trends Genet.
- A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene. Church et al., 2009. PLoS Genet.
- FTO genotype and weight loss in diet and lifestyle interventions: a systematic review and meta-analysis. Xiang et al., 2016. Am J Clin Nutr.
- The economic impact of obesity in the United States. Hammond and Levine, 2010. Diabetes Metab Syndr Obes.
- Fat distribution and mortality: the AGES-Reykjavik Study. Koster et al., 2015. Obesity (Silver Spring).
- Molecular Paths Linking Metabolic Diseases, Gut Microbiota Dysbiosis and Enterobacteria Infections. Serino, 2018. J Mol Biol.
- Gut microbiota, diet, and obesity-related disorders-The good, the bad, and the future challenges. Portune et al., 2017. Mol Nutr Food Res.
- Influence of high-fat diet on gut microbiota: a driving force for chronic disease risk. Murphy, Velazquez, and Herbert, 2015. Curr Opin Clin Nutr Metab Care.
- An obesity-associated gut microbiome with increased capacity for energy harvest. Turnbaugh et al., 2006. Nature.
- New-found link between microbiota and obesity. Chakraborti, 2015. World J Gastrointest Pathophysiol.
- Butyrate: A Double-Edged Sword for Health? Liu et al., 2018. Adv Nutr.
- Obesity-associated low-grade inflammation in type 2 diabetes mellitus: causes and consequences. van Greevenbroek et al., 2013. Neth J Med.
- The Global Epidemic of the Metabolic Syndrome. Saklayen, 2018. Curr Hypertens Rep.
- Insulin resistance: an adaptive mechanism becomes maladaptive in the current environment – an evolutionary perspective. Tsatsoulis et al., 2013. Metabolism.
- Heart disease and stroke statistics–2014 update: a report from the American Heart Association. Go et al., 2014. Circulation.
- Genetic and molecular aspects of hypertension. Padmanabhan, Caulfield, and Dominiczak, 2015. Circ Res.
- Influence of CYP11B2 gene polymorphism on the prevalence of hypertension and the blood pressure in Japanese men: interaction with dietary salt intake. Song et al., 2008. J Nutrigenet Nutrigenomics.
- How Much Added Sugar Are You Consuming? (And Why You Should Care). The Health Sciences Academy
- 4 Effective Steps to Help Break the Sugar Habit. The Health Sciences Academy
- Consumption of added sugars is decreasing in the United States. Welsh et al., 2011. Am J Clin Nutr.
- Sugar consumption and global prevalence of obesity and hypertension: an ecological analysis. Siervo et al., 2014. Public Health Nutr.
- How much sugar is hidden in drinks marketed to children? A survey of fruit juices, juice drinks and smoothies. Boulton et al., 2016. BMJ Open.
- Sugar: World Markets and Trade. USDA, 2017
- Examining the health effects of fructose. Ludwig, 2013. JAMA
- Dietary sugars: their detection by the gut-brain axis and their peripheral and central effects in health and diseases. Ochoa et al., 2015. Eur J Nutr.
- Dietary fructose intolerance, fructan intolerance and FODMAPs. Fedewa and Rao, 2014. Curr Gastroenterol Rep.
- Personal view: food for thought–western lifestyle and susceptibility to Crohn’s disease. The FODMAP hypothesis. Gibson and Shepherd, 2005. Aliment Pharmacol Ther.
- The low FODMAP diet: recent advances in understanding its mechanisms and efficacy in IBS. Staudacher and Whelan, 2017. Gut.
- Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer’s disease. Graham et al., 2016. Sci Rep.
- Body weight gain in rats by a high-fat diet produces chronodisruption in activity/inactivity circadian rhythm. Bravo et al., 2014. Chronobiol Int.
- Hearts from mice fed a non-obesogenic high-fat diet exhibit changes in their oxidative state, calcium and mitochondria in parallel with increased susceptibility to reperfusion injury. Littlejohns et al., 2014. PLoS One.
- High-fat diet-induced memory impairment in triple-transgenic Alzheimer’s disease (3xTgAD) mice is independent of changes in amyloid and tau pathology. Knight et al., 2014. Neurobiol Aging.
- Diet and Health: Implications for Reducing Chronic Disease Risk. National Research Council (US) Committee on Diet and Health, 1989. National Academies Press (US).
- Effects of dietary fat profile on gut permeability and microbiota and their relationships with metabolic changes in mice. Lam et al., 2015. Obesity (Silver Spring).
- Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1. Wu et al., 2013. Nature.
- Evidence for a link between gut microbiota and hypertension in the Dahl rat. Mell et al., 2015. Physiol Genomics.
- Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells. Kleinewietfeld et al., 2013. Nature.
- Gut dysbiosis is linked to hypertension. Yang et al., 2015. Hypertension.
- High dietary salt intake exacerbates Helicobacter pylori-induced gastric carcinogenesis. Gaddy et al., 2013. Infect Immun.
- Helicobacter pylori adaptation in vivo in response to a high-salt diet. Loh et al., 2015. Infect Immun.
- Dietary salt intake and risk of gastric cancer. D'Elia, Galletti, and Strazzullo, 2014. Cancer Treat Res.
- The food safety impact of salt and sodium reduction initiatives. Christopher and Wallace, 2014. Perspect Public Health.
- National Diet and Nutrition Survey – Assessment of dietary sodium in adults (agdes 19 to 64 years) in England, 2011. Department of Health.
- Scientific Opinion on the evaluation of allergenic foods and food ingredients for labelling purposes. EFSA, 2014.
- What is unique about the IgE response? Xiong, Curotto de Lafaille, and Lafaille, 2012. Adv Immunol.
- Food allergy. Renz et al., 2018. Nat Rev Dis Primers.
- Anaphylaxis in food allergy. Pesek and Jones, 2015. Chem Immunol Allergy.
- Extracellular vesicles in parasitic diseases. Marcilla et al., 2014. J Extracell Vesicles.
- Allergens, sources, particles, and molecules: Why do we make IgE responses? Woodfolk et al., 2015. Allergol Int.
- Oral food challenge: safety, adherence to guidelines and predictive value of skin prick testing. Calvani et al., 2012. Pediatr Allergy Immunol.
- Food protein-induced enterocolitis syndrome and allergic proctocolitis. Nowak-Węgrzyn, 2015. Allergy Asthma Proc.
- Gut permeability and food allergies. Perrier and Corthésy, 2011. Clin Exp Allergy.
- Food allergens affect the intestinal tight junction permeability in inducing intestinal food allergy in rats. Chen et al., 2014. Asian Pac J Allergy Immunol.
- Review article: the aetiology, diagnosis, mechanisms and clinical evidence for food intolerance. Lomer, 2015. Aliment Pharmacol Ther.
- Lactose Intolerance in Adults: Biological Mechanism and Dietary Management. Deng et al., 2015. Nutrients.
- Milk Intolerance, Beta-Casein and Lactose. Pal et al., 2015. Nutrients.
- Review article: the diagnosis and management of food allergy and food intolerances. Turnbull, Adams, and Gorard, 2015. Aliment Pharmacol Ther.
- The clinical consequences of sucrase-isomaltase deficiency. Cohen, 2016. Mol Cell Pediatr.
- Nitrate intolerance. Asero, 2000. Allergy.
- Food intolerance and allergy: increased incidence or contemporary inadequate diets? Skypala and Vlieg-Boerstra, 2014. Curr Opin Clin Nutr Metab Care.
- Review article: the aetiology, diagnosis, mechanisms and clinical evidence for food intolerance. Lomer, 2015. Aliment Pharmacol Ther.
- Milk Intolerance, Beta-Casein and Lactose. Pal et al., 2015. Nutrients.
- Histamine and histamine intolerance. Maintz and Novak, 2007. Am J Clin Nutr.
- Significance of salicylate intolerance in diseases of the lower gastrointestinal tract. Raithel et al., 2005. J Physiol Pharmacol.
- The effect of dietary glutamate on fibromyalgia and irritable bowel symptoms. Holton et al., 2012. Clin Exp Rheumatol.
- NIH consensus development conference statement: Lactose intolerance and health. Suchy et al., 2010. NIH Consens State Sci Statements.
- Mastication of almonds: effects of lipid bioaccessibility, appetite, and hormone response. Cassady et al., 2009. Am J Clin Nutr.
- Nutrient intake and gastrointestinal disorders related to masticatory performance in the edentulous elderly. Brodeur et al., 1993. J Prosthet Dent.
- Increased number of chews during a fixed-amount meal suppresses postprandial appetite and modulates glycemic response in older males. Zhu, Hsu, and Hollis, 2014. Physiol Behav.
- Thorough Mastication Prior to Swallowing Increases Postprandial Satiety and the Thermic Effect of a Meal in Young Women. Komai et al., 2016. J Nutr Sci Vitaminol (Tokyo).
- Effect of bite size and oral processing time of a semisolid food on satiation. Zijlstra et al., 2009. Am J Clin Nutr.
- Biotechnological Processes in Microbial Amylase Production. Gopinath et al., 2017. Biomed Res Int.
- Starch Digestion-Related Amylase Genetic Variant Affects 2-Year Changes in Adiposity in Response to Weight-Loss Diets: The POUNDS Lost Trial. Heianza et al., 2017. Diabetes.
- Diet and the evolution of human amylase gene copy number variation. Perry et al., 2007. Nat Genet.
- Total antioxidant capacity of saliva and dental caries. Ahmadi-Motamayel et al., 2013. Med Oral Patol Oral Cir Bucal.
- Risk factors for gastroesophageal reflux disease: the role of diet. Jarosz and Taraszewska, 2014. Prz Gastroenterol.
- Gastric reacidification with betaine HCl in healthy volunteers with rabeprazole-induced hypochlorhydria. Yago et al., 2013. Mol Pharm.
- Comparing 3-hour pH monitoring in esophagus with 24-hour pH monitoring to diagnose GERD. Guijian, Lili, and Yulan, 2010. Hepatogastroenterology.
- Magnitude and duration of elevated gastric pH in patients infected with human immunodeficiency virus after administration of chewable, dispersible, buffered didanosine tablets. DePestel et al., 2004. Pharmacotherapy.
- Structure, function and applications of carbonic anhydrase isozymes. Imtaiyaz Hassan et al., 2013. Bioorg Med Chem.
- Potassium channel KCNJ15 is required for histamine-stimulated gastric acid secretion. Yuan et al., 2015. Am J Physiol Cell Physiol.
- Chronic pancreatitis and persistent steatorrhea: what is the correct dose of enzymes? Domínguez-Muñoz, 2011. Clin Gastroenterol Hepatol.
- Systematic review: efficacy and safety of pancreatic enzyme supplements for exocrine pancreatic insufficiency. Taylor et al., 2010. Aliment Pharmacol Ther.
- Gallstones. Njeze, 2013. Niger J Surg.
- High-fat diet reduces the formation of butyrate, but increases succinate, inflammation, liver fat and cholesterol in rats, while dietary fibre counteracts these effects. Jakobsdottir et al., 2013. PLoS One.
- Soluble dietary fiber protects against cholesterol gallstone formation. Schwesinger et al., 1999. Am J Surg.
- Risk factors for gallstone formation during rapid loss of weight. Yang et al., 1992. Dig Dis Sci.
- Role of diet in cholesterol gallstone formation. Méndez-Sánchez et al., 2007. Clin Chim Acta.
- Cholesterol-lowering properties of different pectin types in mildly hyper-cholesterolemic men and women. Brouns et al., 2012. Eur J Clin Nutr.
- Molecular Properties of Guar Gum and Pectin Modify Cecal Bile Acids, Microbiota, and Plasma Lipopolysaccharide-Binding Protein in Rats. Ghaffarzadegan et al., 2016. PLoS One.
- Palm Oil Consumption Increases LDL Cholesterol Compared with Vegetable Oils Low in Saturated Fat in a Meta-Analysis of Clinical Trials. Sun et al., 2015. J Nutr.
- The effect of long-term intake of cis unsaturated fats on the risk for gallstone disease in men: a prospective cohort study. Tsai et al., 2004. Ann Intern Med.
- Cocoa butter and safflower oil elicit different effects on hepatic gene expression and lipid metabolism in rats. Gustavsson et al., 2009. Lipids.
- Dietary fibre intake and risk of cardiovascular disease: systematic review and meta-analysis. Threapleton et al., 2013. BMJ.
- Potential Benefits of Dietary Fibre Intervention in Inflammatory Bowel Disease. Wong, Harris, and Ferguson, 2016. Int J Mol Sci.
- Dietary reference values. EFSA, 2017. Refrieved Jan 2019.
- Soluble maize fibre affects short-term calcium absorption in adolescent boys and girls: a randomised controlled trial using dual stable isotopic tracers. Whisner et al., 2014. Br J Nutr.
- Effects of dietary fiber and its components on metabolic health. Lattimer and Haub, 2010.
- Gut microbiota richness promotes its stability upon increased dietary fibre intake in healthy adults. Tap et al., 2015. Environ Microbiol.
- Nutritional protective mechanisms against gut inflammation. Viladomiu et al., 2013. J Nutr Biochem.
- A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility. Desai et al., 2016. Cell.
- Resveratrol Attenuates Trimethylamine-N-Oxide (TMAO)-Induced Atherosclerosis by Regulating TMAO Synthesis and Bile Acid Metabolism via Remodeling of the Gut Microbiota. Chen et al., 2016. MBio.
- Fruit and vegetable consumption and sports participation among UK Youth. McAloney et al., 2014. Int J Public Health
- Saturated Fatty Acids and Cardiovascular Disease: Replacements for Saturated Fat to Reduce Cardiovascular Risk. Briggs, Petersen, and Kris-Etherton, 2017. Healthcare (Basel).
- Saturated Fats Compared With Unsaturated Fats and Sources of Carbohydrates in Relation to Risk of Coronary Heart Disease: A Prospective Cohort Study. Li et al., 2015. J Am Coll Cardiol.
- The Evidence for Saturated Fat and for Sugar Related to Coronary Heart Disease. DiNicolantonio, Lucan, and O'Keefe, 2016. Prog Cardiovasc Dis.
- Dietary fats and coronary heart disease. Willett, 2012. J Intern Med.
- Effects of dietary fat profile on gut permeability and microbiota and their relationships with metabolic changes in mice. Lam et al., 2015. Obesity (Silver Spring).
- Long-term intake of dietary fat and risk of ulcerative colitis and Crohn’s disease. Ananthakrishnan et al., 2014. Gut.
- Polyunsaturated fatty acids support epithelial barrier integrity and reduce IL-4 mediated permeability in vitro. Willemsen et al., 2008. Eur J Nutr.
- Impact of dietary fat on gut microbiota and low-grade systemic inflammation: mechanisms and clinical implications on obesity. Cândido et al., 2018. Int J Food Sci Nutr.
- USDA Food Composition Databases. United States Department of Agriculture. Retrieved Jan 2020
- Feasibility and antihypertensive effect of replacing regular salt with mineral salt -rich in magnesium and potassium- in subjects with mildly elevated blood pressure. Sarkkinen et al., 2011. Nutr J.
- Dietary Impact of Adding Potassium Chloride to Foods as a Sodium Reduction Technique. van Buren et al., 2016. Nutrients.
- The stress-buffering effect of acute exercise: Evidence for HPA axis negative feedback. Zschucke et al., 2015. Psychoneuroendocrinology.
- Intervention to increase physical activity in irritable bowel syndrome shows long-term positive effects. Johannesson et al., 2015. World J Gastroenterol.
- Diet, exercise and gut mucosal immunity. Valdés-Ramos et al., 2010. Proc utr Soc.
- Exercise and associated dietary extremes impact on gut microbial diversity. Clarke et al., 2014. Gut.
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- Increased objectively assessed vigorous-intensity exercise is associated with reduced stress, increased mental health and good objective and subjective sleep in young adults. Gerber et al., 2014. Physiol Behav.
- Exercise increases Rho-kinase activity and insulin signaling in skeletal muscle. Muñoz et al., 2018. J Cell Physiol.
- Antidepressant effects of exercise are produced via suppression of hypocretin/orexin and melanin-concentrating hormone in the basolateral amygdala. Kim et al., 2015. Neurobiol Dis.
- Comparing quality-adjusted life expectancy at different levels of physical activity. Jia and Lubetkin, 2014. J Phys Act Health.
- Potential benefits and hazards of physical activity and exercise on the gastrointestinal tract. Peters et al., 2001. Gut.
- The microbiota: an exercise immunology perspective. Bermon et al., 2015. Exerc Immunol Rev.
- Exercise is a Novel Promoter of Intestinal Health and Microbial Diversity. Campbell and Wisniewski PJ 2nd., 2017. Exerc Sport Sci Rev.
- The Effect of Diet and Exercise on Intestinal Integrity and Microbial Diversity in Mice. Campbell et al., 2016. PLoS One.
- Gut microbiota composition in male rat models under different nutritional status and physical activity and its association with serum leptin and ghrelin levels. Queipo-Ortuño et al., 2013. PLoS One.
- Diet and exercise orthogonally alter the gut microbiome and reveal independent associations with anxiety and cognition. Kang et al., 2014. Mol Neurodegener.
- Sleep Disturbance, Sleep Duration, and Inflammation: A Systematic Review and Meta-Analysis of Cohort Studies and Experimental Sleep Deprivation. Irwin, Olmstead, and Carroll, 2016. Biol Psychiatry.
- Metabolic effects of sleep disruption, links to obesity and diabetes. Nedeltcheva and Scheer, 2014. Curr Opin Endocrinol Diabetes Obes.
- Neurobiology of the sleep-wake cycle: sleep architecture, circadian regulation, and regulatory feedback. Fuller, Gooley, and Saper, 2006. J Biol Rhythms.
- Daily Eating Patterns and Their Impact on Health and Disease. Zarrinpar, Chaix, and Panda, 2016. Trends Endocrinol Metab.
- Sleep: a health imperative. Luyster et al., 2012. Sleep.
- A preliminary examination of gut microbiota, sleep, and cognitive flexibility in healthy older adults. Anderson et al., 2017. Sleep Med.
- Effect of sleep quality on symptoms of irritable bowel syndrome. Goldsmith and Levin, 1993. Dig Dis Sci.
- Unmet Needs in IBD: the Case of Fatigue. Hindryckx et al., 2017. Clin Rev Allergy Immunol.
- Sleep, recovery, and metaregulation: explaining the benefits of sleep. Vyazovskiy, 2015. Nat Sci Sleep.
- Circadian disorganization alters intestinal microbiota. Voigt et al., 2014. PLoS One.
- The Circadian Clock Mutation Promotes Intestinal Dysbiosis. Voigt et al., 2016. Alcohol Clin Exp Res.
- Sleep disruption secondary to overnight call shifts is associated with irritable bowel syndrome in residents: a cross-sectional study. Wells, Roth, and Chande, 2012. Am J Gastroenterol.
- An initial report of sleep disturbance in inactive inflammatory bowel disease. Keefer et al., 2006. J Clin Sleep Med.
- Expert consensus document. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. Hill et al., 2014. Nat Rev Gastroenterol Hepatol.
- Probiotic intervention has strain-specific anti-inflammatory effects in healthy adults. Kekkonen et al., 2008. World J Gastroenterol.
- Probiotic potential of selected lactic acid bacteria strains isolated from Brazilian kefir grains. Leite et al., 2015. J Dairy Sci.
- Microorganisms with claimed probiotic properties: an overview of recent literature. Fijan, 2014. Int J Environ Res Public Health.
- A review of the advancements in probiotic delivery: Conventional vs. non-conventional formulations for intestinal flora supplementation. Govender et al., 2014. AAPS PharmSciTech.
- Pilot-scale production and viability analysis of freeze-dried probiotic bacteria using different protective agents. Savini et al., 2010. Nutrients.
- Probiotics in food: Health and nutritional properties and guidelines for evaluation. FAO/WHO, 2002.
- Outcome of a public consultation on the draft guidance of the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) on the scientific requirements for health claims related to the immune system, the gastrointestinal tract and defence against pathogenic microorganisms. EFSA, 2016.
- Beneficial effects of long-term consumption of a probiotic combination of Lactobacillus casei Shirota and Bifidobacterium breve Yakult may persist after suspension of therapy in lactose-intolerant patients. Almeida et al., 2012. Nutr Clin Pract.
- Non-dairy probiotic beverages: the next step into human health. Gawkowski and Chikindas, 2013. Benef Microbes.
- Competition for adhesion between probiotics and human gastrointestinal pathogens in the presence of carbohydrate. Lee and Puong, 2002. Br J Nutr.
- Probiotic supplementation influences faecal short chain fatty acids in infants at high risk for eczema. Kim et al., 2015. Benef Microbes.
- Probiotics, prebiotics and immunomodulation of gut mucosal defences: homeostasis and immunopathology. Hardy et al., 2013. Nutrients.
- Novel bacteriocins from lactic acid bacteria (LAB): various structures and applications. Perez, Zendo, and Sonomoto, 2014. Microb Cell Fact.
- Probiotic Escherichia coli Nissle 1917 inhibits leaky gut by enhancing mucosal integrity. Ukena et al., 2007. PLoS One.
- Probiotic mechanisms of action. Bermudez-Brito et al., 2012. Ann Nutr Metab.
- Antagonistic activities of lactobacilli and bifidobacteria against microbial pathogens. Servin, 2004. FEMS Microbiol Rev.
- The effect of Lactobacillus rhamnosus on enterohemorrhagic Escherichia coli infection of human intestinal cells in vitro. Hirano et al., 2003. Microbiol Immunol.
- Beneficial metabolic effects of a probiotic via butyrate-induced GLP-1 hormone secretion. Yadav et al., 2013. J Biol Chem.
- Nutritional protective mechanisms against gut inflammation. Viladomiu et al., 2013. J Nutr Biochem.
- Role of Toll-like receptors in the development of immunotolerance mediated by probiotics. Gómez-Llorente, Muñoz, and Gil, 2010. Proc Nutr Soc.
- Differential Toll-like receptor recognition and induction of cytokine profile by Bifidobacterium breve and Lactobacillus strains of probiotics. Plantinga et al., 2011. Clin Vaccine Immunol.
- Probiotic genomic DNA reduces the production of pro-inflammatory cytokine tumor necrosis factor-alpha. Kim et al., 2012. FEMS Microbiol Lett.
- A randomized controlled trial to test the effect of multispecies probiotics on cognitive reactivity to sad mood. Steenbergen et al., 2015. Brain Behav Immun.
- Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in rats and human subjects. Messaoudi et al., 2011. Br J Nutr.
- Systematic review of evidence to support the theory of psychobiotics. Romijn and Rucklidge, 2015. Nutr Rev.
- Bacterial neuroactive compounds produced by psychobiotics. Wall et al., 2014. Adv Exp Med Biol.
- Stress-induced plasticity of GABAergic inhibition. Maguire, 2014. Front Cell Neurosci.
- Technological and safety properties of newly isolated GABA-producing Lactobacillus futsaii strains. Sanchart et al., 2016. J Appl Microbiol.
- Daily intake of fermented milk with Lactobacillus casei strain Shirota reduces the incidence and duration of upper respiratory tract infections in healthy middle-aged office workers. Shida et al., 2017. Eur J Nutr.
- Effectiveness of probiotics in type 2 diabetes: a meta-analysis. Kasinska and Drzewoski, 2015. Pol Arch Med Wewn.
- Effects of probiotics for the treatment of atopic dermatitis: a meta-analysis of randomized controlled trials. Kim et al., 2014. Ann Allergy Asthma Immunol.
- The efficacy and safety of probiotics in people with cancer: a systematic review. Redman, Ward, and Phillips, 2014. Ann Oncol.
- Probiotic supplementation in children with autism spectrum disorder. Srinivasjois, Rao, and Patole, 2015. Arch Dis Child.
- Functions of the skin microbiota in health and disease. Sanford and Gallo, 2013. Semin Immunol.
- Health effects of probiotics on the skin. Roudsari et al., 2015. Crit Rev Food Sci Nutr.
- Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability. Cani et al., 2009. Gut.
- Probiotics and Prebiotics: Present Status and Future Perspectives on Metabolic Disorders. Yoo and Kim, 2016. Nutrients.
- Dietary modulation of the human colonic microbiota: updating the concept of prebiotics. Gibson et al., 2004. Nutr Res Rev.
- Fiber and prebiotics: mechanisms and health benefits. Slavin, 2013. Nutrients.
- Inulin, a flexible oligosaccharide I: Review of its physicochemical characteristics. Mensink et al., 2015. Carbohydr Polym.
- Fermentation properties and potential prebiotic activity of Bimuno® galacto-oligosaccharide (65 % galacto-oligosaccharide content) on in vitro gut microbiota parameters. Grimaldi et al., 2016. Br J Nutr.
- Prebiotic evaluation of a novel galactooligosaccharide mixture produced by the enzymatic activity of Bifidobacterium bifidum NCIMB 41171, in healthy humans: a randomized, double-blind, crossover, placebo-controlled intervention study. Depeint et al., 2008. Am J Clin Nutr.
- Synthesis of novel bioactive lactose-derived oligosaccharides by microbial glycoside hydrolases. Díez-Municio et al., 2014. Microb Biotechnol.
- Gut microbiota role in irritable bowel syndrome: New therapeutic strategies. Distrutti et al., 2016. World J Gastroenterol.
- Clinical trial: the effects of a trans-galactooligosaccharide prebiotic on faecal microbiota and symptoms in irritable bowel syndrome. Silk et al., 2009. Aliment Pharmacol Ther.
- Probiotics and prebiotics in the management of irritable bowel syndrome: a review of recent clinical trials and systematic reviews. Whelan, 2011. Curr Opin Clin Nutr Metab Care.
- Barcoded pyrosequencing reveals that consumption of galactooligosaccharides results in a highly specific bifidogenic response in humans. Davis et al., 2011. PLoS One.
- Prebiotic fiber modulation of the gut microbiota improves risk factors for obesity and the metabolic syndrome. Parnell and Reimer, 2012. Gut Microbes.
- Technology and potential applications of probiotic encapsulation in fermented milk products. Iravani, Korbekandi, and Mirmohammadi, 2015. J Food Sci Technol.
- Therapeutic effect of Lactobacillus acidophilus-SDC 2012, 2013 in patients with irritable bowel syndrome. Sinn et al., 2008. Dig Dis Sci.
- A randomized double-blind placebo-controlled clinical trial on efficacy and safety of association of simethicone and Bacillus coagulans (Colinox®) in patients with irritable bowel syndrome. Urgesi et al., 2014. Eur Rev Med Pharmacol Sci.
- The efficacy of a synbiotic containing Bacillus Coagulans in treatment of irritable bowel syndrome: a randomized placebo-controlled trial. Rogha, Esfahani, and Zargarzadeh, 2014. Gastroenterol Hepatol Bed Bench.
- Bifidobacterium bifidum as an example of a specialized human gut commensal. Turroni et al., 2014. Front Microbiol.
- Randomised clinical trial: Bifidobacterium bifidum MIMBb75 significantly alleviates irritable bowel syndrome and improves quality of life–a double-blind, placebo-controlled study. Guglielmetti et al., 2011. Aliment Pharmacol Ther.
- A gastroenterologist’s guide to probiotics. Ciorba, 2012. Clin Gastroenterol Hepatol.
- The Effect Of Probiotic Fermented Milk That Includes Bifidobacterium Lactis Cncm I-2494 On The Reduction Of Gastrointestinal Discomfort And Symptoms In Adults: A Narrative Review. Waitzberg et al., 2015. Nutr Hosp.
- The Science behind the Probiotic Strain Bifidobacterium animalis subsp. lactis BB-12(®). Jungersen et al., 2014. Microorganisms.
- Colonic gas homeostasis: Mechanisms of adaptation following HOST-G904 galactooligosaccharide use in humans. Mego et al., 2017. Neurogastroenterol Motil.
- Prebiotic digestion and fermentation. Cummings, Macfarlane, and Englyst, 2001. Am J Clin Nutr.
- Kefir improves lactose digestion and tolerance in adults with lactose maldigestion. Hertzler and Clancy, 2003.
- Vitamin D deficiency. Holick, 2007. N Engl J Med.
- The human environment and the vitamin D compromise: Scotland as a case study in human biocultural adaptation and disease susceptibility. Chaplin and Jablonski, 2013. Hum Biol.
- Relationships of serum 25-hydroxyvitamin D to bone mineral density and serum parathyroid hormone and markers of bone turnover in older persons. Kuchuk et al., 2009. J Clin Endocrinol Metab.
- Vitamin D levels and deficiency with different occupations: a systematic review. Sowah et al., 2017. BMC Public Health.
- A mathematical model for seasonal variability of vitamin D due to solar radiation. Krzyscin, Jaroslawski, and Sobolewsi, 2011. J Photochem Photobiol B.
- Scientific Advisory Committee on Nutrition (SACN). UK government. Retrieved Jan 2020.
- Skin color is relevant to vitamin D synthesis. Libon, Cavalier, and Nikkels, 2013. Dermatology.
- A Practical Approach to Vitamin D Deficiency and Rickets. Allgrove and Shaw, 2015. Endocr Dev.
- Casimir Funk: his discovery of the vitamins and their deficiency disorders. Piro et al., 2010. Ann Nutr Metab.
- Vitamin D status in irritable bowel syndrome and the impact of supplementation on symptoms: what do we know and what do we need to know? Williams, Williams, and Corfe, 2018. Eur J Clin Nutr.
- Vitamin D supplementation in adolescents with irritable bowel syndrome: Is it useful? A randomized controlled trial. El Amrousy et al., 2018. Saudi J Gastroenterol.
- Vitamin D prevents hypoxia/reoxygenation-induced blood-brain barrier disruption via vitamin D receptor-mediated NF-kB signaling pathways. Won et al., 2015. PLoS One.
- Relevance of vitamin D receptor target genes for monitoring the vitamin D responsiveness of primary human cells. Vukić et al., 2015. PLoS One.
- The Vitamin D Receptor, Inflammatory Bowel Diseases, and Colon Cancer. Lu et al., 2012. Curr Colorectal Cancer Rep.
- Vitamin D deficiency in children with inflammatory bowel disease. Levin et al., 2011. Dig Dis Sci.
- Gut microbiota interactions with the immunomodulatory role of vitamin D in normal individuals. Luthold et al., 2017. Metabolism.
- Vitamin D regulates the gut microbiome and protects mice from dextran sodium sulfate-induced colitis. Ooi et al., 2013. J Nutr.
- Dietary reference values for vitamin D. EFSA, 2016.
- Scientific Opinion on the Tolerable Upper Intake Level of vitamin D. EFSA, 2012.
- Tolerable Upper Intake Levels ofr Vitamins and Minerals. Scientific Committee on Food, 2006.
- Vitamin D: deficiency, sufficiency and toxicity. Alshahrani and Aljohani, 2013. Nutrients.
- The discovery of the visual function of vitamin A. Wolf, 2001. J Nutr.
- The evidence for a beneficial role of vitamin A in multiple sclerosis. Fragoso, Stoney, and McCaffery, 2014. CNS Drugs.
- Vitamin effects on the immune system: vitamins A and D take centre stage. Mora, Iwata, and von Adrian, 2008. Nat Rev Immunol.
- The pleiotropic role of vitamin A in regulating mucosal immunity. Sirisinha, 2015. Asian Pac J Allergy Immunol.
- Metabolism and functional effects of plant-derived omega-3 fatty acids in humans. Baker et al., 2016. Prog Lipid Res.
- Dietary omega 3 fatty acids and the developing brain. Innis, 2008. Brain Res.
- Omega-3 Fatty Acids and Primary and Secondary Prevention of Cardiovascular Disease. Cao et al., 2015. Cell Biochem Biophys.
- Omega-3 fatty acids and inflammation: a perspective on the challenges of evaluating efficacy in clinical research. Skulas-Ray, 2015. Prostaglandins Other Lipid Mediat.
- Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation. Yan et al., 2013. Immunity.
- CD4(+) T-cell activation is differentially modulated by bacteria-primed dendritic cells, but is generally down-regulated by n-3 polyunsaturated fatty acids. Brix et al., 2010. Immunity.
- Dietary ω3 fatty acid exerts anti-allergic effect through the conversion to 17,18-epoxyeicosatetraenoic acid in the gut. Kunisawa et al., 2015. Sci Rep.
- Fatty acid profile and affective dysregulation in irritable bowel syndrome. Kilkens et al., 2004. Lipids.
- Polyunsaturated Fatty Acids and Their Derivatives: Therapeutic Value for Inflammatory, Functional Gastrointestinal Disorders, and Colorectal Cancer. Michalak, Mosinska, and Fichna, 2016. Front Pharmacol.
- N-3 PUFAs attenuate ischemia/reperfusion induced intestinal barrier injury by activating I-FABP-PPARγ pathway. Wang et al., 2012. Clin Nutr.
- Understanding the Impact of Omega-3 Rich Diet on the Gut Microbiota. Noriega et al., 2016. Case Rep Med.
- N-3 Polyunsaturated Fatty Acids (PUFAs) Reverse the Impact of Early-Life Stress on the Gut Microbiota. Pusceddu et al., 2015. PLoS One.
- Seroreactivity against Saccharomyces cerevisiae in patients with Crohn’s disease and celiac disease - PMC (nih.gov)
- [Anti-Saccharomyces cerevisiae antibodies in patients with Crohn's disease] - PubMed (nih.gov)
- IgE, IgA, and IgG responses to common yeasts in atopic patients - PubMed (nih.gov)
- Allergenic cross-reactivity of yeasts - PubMed (nih.gov)
- Effects of Oral Supplementation With Methylsulfonylmethane on Skin Health and Wrinkle Reduction | Natural Medicine Journal
- Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement - PMC (nih.gov)
- The anti-inflammatory effects of methylsulfonylmethane on lipopolysaccharide-induced inflammatory responses in murine macrophages - PubMed (nih.gov)
- Zinc lozenges and the common cold: a meta-analysis comparing zinc acetate and zinc gluconate, and the role of zinc dosage - Harri Hemilä, 2017 (sagepub.com)
- Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data (bmj.com)
- Elderberry flavonoids bind to and prevent H1N1 infection in vitro - PubMed (nih.gov)
- The Effect of Cold Showering on Health and Work: A Randomized Controlled Trial - PMC (nih.gov)
- 4271434.pdf (harvard.edu)
- Assessment of spatio-temporal gait parameters from trunk accelerations during human walking - PubMed (nih.gov)
- (PDF) Chen et al. 2015_Supplemental Information (researchgate.net)
- De Roos, A. J., et al. (2013). Glyphosate and celiac disease: A study of a potential environmental trigger. Environmental Health, 12(1), 79
- De Roos, A. J., et al. (2013). Glyphosate and celiac disease: A study of a potential environmental trigger. Environmental Health, 12(1), 79.
- Environmental Working Group (EWG). (2018). Breakfast with a Dose of Roundup? Retrieved from https://www.ewg.org/childrenshealth/monsanto-weedkiller-still-contaminates-foods-marketed-to-children/
- Ma, B., et al. (2019). Glyphosate disrupts gut microbiome and causes gut pathology in fish. Nature, 666(8049), 146-150.
- Benbrook, C. M. (2016). Trends in glyphosate herbicide use in the United States and globally. Environmental Sciences Europe, 28(1), 3.
- Bøhn, T., Cuhra, M., Traavik, T., Sanden, M., Fagan, J., & Primicerio, R. (2014). Compositional differences in soybeans on the market: glyphosate accumulates in Roundup Ready GM soybeans. Food Chemistry, 153, 207-215.
- Motavalli, P. P., R. D. Burcham, L. S. Young, J. A. Andresen, and A. Mall. (2017). Glyphosate residues in Midwestern U.S. streams and rivers: Results of sampled storm events. Journal of Environmental Protection, 8, 1334-1345.
- Qu, C., et al. (2019). Glyphosate and AMPA distribution in wind-eroded sediment derived from loess soil. Environmental Science and Pollution Research, 26(17), 17205-17214.
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